DNA damage response- and JAK-dependent regulation of PD-L1 expression in head and neck squamous cell carcinoma (HNSCC) cells exposed to 5-fluorouracil (5-FU)

OBJECTIVES: The immune checkpoint molecule PD-L1 (CD274) is a crucial regulator of the tumor immune response. Its expression has been reported in the therapeutic context in Head and Neck Squamous Cell Carcinoma (HNSCC), but it remains unclear how therapeutically approved molecules regulate PD-L1 exp...

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Detalhes bibliográficos
Publicado no:Transl Oncol
Main Authors: Lailler, Claire, Lamuraglia, Michele, Racine, Floriane, Louandre, Christophe, Godin, Corinne, Chauffert, Bruno, Galmiche, Antoine, Saidak, Zuzana
Formato: Artigo
Idioma:Inglês
Publicado em: Neoplasia Press 2021
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8111315/
https://ncbi.nlm.nih.gov/pubmed/33951601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tranon.2021.101110
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