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M2 macrophage-derived exosomal long non-coding RNA AGAP2-AS1 enhances radiotherapy immunity in lung cancer by reducing microRNA-296 and elevating NOTCH2

Long noncoding RNAs (lncRNAs) and microRNAs (miRNAs) play vital roles in human diseases. We aimed to identify the effect of the lncRNA AGAP2 antisense RNA 1 (AGAP2-AS1)/miR-296/notch homolog protein 2 (NOTCH2) axis on the progression and radioresistance of lung cancer. Expression of AGAP2-AS1, miR-2...

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Dades bibliogràfiques
Publicat a:Cell Death Dis
Autors principals: Zhang, Fuquan, Sang, Yonghua, Chen, Donglai, Wu, Xuejie, Wang, Xiaofan, Yang, Wentao, Chen, Yongbing
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2021
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8110970/
https://ncbi.nlm.nih.gov/pubmed/33972506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-021-03700-0
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