Allopurinol ameliorates high fructose diet induced hepatic steatosis in diabetic rats through modulation of lipid metabolism, inflammation, and ER stress pathway

Excess fructose consumption contributes to development obesity, metabolic syndrome, and nonalcoholic fatty liver disease (NAFLD). Uric acid (UA), a metabolite of fructose metabolism, may have a direct role in development of NAFLD, with unclear mechanism. This study aimed to evaluate role of fructose...

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Published in:Sci Rep
Main Authors: Cho, In-Jin, Oh, Da-Hee, Yoo, Jin, Hwang, You-Cheol, Ahn, Kyu Jeung, Chung, Ho-Yeon, Jeong, Soung Won, Moon, Ju-Young, Lee, Sang-Ho, Lim, Sung-Jig, Jeong, In-Kyung
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2021
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8110790/
https://ncbi.nlm.nih.gov/pubmed/33972568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-88872-7
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