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Molnupiravir promotes SARS-CoV-2 mutagenesis via the RNA template
The RNA-dependent RNA polymerase of the severe acute respiratory syndrome coronavirus 2 is an important target in current drug development efforts for the treatment of coronavirus disease 2019. Molnupiravir is a broad-spectrum antiviral that is an orally bioavailable prodrug of the nucleoside analog...
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| Vydáno v: | J Biol Chem |
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| Hlavní autoři: | , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Society for Biochemistry and Molecular Biology
2021
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8110631/ https://ncbi.nlm.nih.gov/pubmed/33989635 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbc.2021.100770 |
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