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Hepatic Manifestations of 3-Hydroxy-3-Methylglutaryl-Coenzyme-A Lyase Deficiency in Saudi Patients: Experience of a Tertiary Care Center

3-Hydroxy-3-methylglutaryl-coenzyme-A lyase (HMGCL) deficiency, a rare autosomal recessive disorder, is caused by a homozygous or compound heterozygous mutation in the HMGCL gene (chromosome 1p36.11). HMGCL catalyzes the final step of leucine degradation and plays a key role in ketone body formation...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:J Pediatr Genet
Päätekijät: Holdar, Sinan, Rahbeeni, Zuhair, Ramzan, Khushnooda, Imtiaz, Faiqa
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Georg Thieme Verlag KG 2021
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC8110366/
https://ncbi.nlm.nih.gov/pubmed/33996180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1055/s-0040-1714698
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