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Matrix metalloproteinase (MMP)-degradable tissue engineered periosteum coordinates allograft healing via early stage recruitment and support of host neurovasculature

Despite serving as the clinical “gold standard” treatment for critical size bone defects, decellularized allografts suffer from long-term failure rates of ~60% due to the absence of the periosteum. Stem and osteoprogenitor cells within the periosteum orchestrate autograft healing through host cell r...

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Bibliografske podrobnosti
izdano v:Biomaterials
Main Authors: Li, Yiming, Hoffman, Michael D., Benoit, Danielle S.W.
Format: Artigo
Jezik:Inglês
Izdano: 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC8110201/
https://ncbi.nlm.nih.gov/pubmed/33271450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2020.120535
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