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ORAI1 establishes resistance to SARS-CoV-2 infection by regulating tonic type I interferon signaling

ORAI1 and STIM1 are the critical mediators of store-operated Ca(2+) entry by acting as the pore subunit and an endoplasmic reticulum-resident signaling molecule, respectively. In addition to Ca(2+) signaling, STIM1 is also involved in regulation of a cytosolic nucleic acid sensing pathway. Using ORA...

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Bibliografische gegevens
Gepubliceerd in:bioRxiv
Hoofdauteurs: Wu, Beibei, Ramaiah, Arunachalam, Garcia, Gustavo, Gwack, Yousang, Arumugaswami, Vaithilingaraja, Srikanth, Sonal
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Cold Spring Harbor Laboratory 2021
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8109209/
https://ncbi.nlm.nih.gov/pubmed/33972946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/2021.05.04.442548
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