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The temperature-dependent conformational ensemble of SARS-CoV-2 main protease (M(pro))
The COVID-19 pandemic, instigated by the SARS-CoV-2 coronavirus, continues to plague the globe. The SARS-CoV-2 main protease, or M(pro), is a promising target for development of novel antiviral therapeutics. Previous X-ray crystal structures of M(pro) were obtained at cryogenic temperature or room t...
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| Publicado no: | bioRxiv |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8109201/ https://ncbi.nlm.nih.gov/pubmed/33972941 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/2021.05.03.437411 |
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