5-Lipoxygenase inhibition reduces inflammation and neuronal apoptosis via AKT signaling after subarachnoid hemorrhage in rats

Early brain injury (EBI) is a major contributor to the high mortality and morbidity after subarachnoid hemorrhage (SAH). Inflammatory responses and neuronal apoptosis are important causes of EBI. Because 5- lipoxygenase (5-LOX) is known to be involved various central nervous system diseases, we inve...

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Bibliografiske detaljer
Udgivet i:Aging (Albany NY)
Main Authors: Liu, Liu, Zhang, Ping, Zhang, Zhaosi, Liang, Yidan, Chen, Hong, He, Zhaohui, Sun, Xiaochuan, Guo, Zongduo, Deng, Yongbing
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals 2021
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8109136/
https://ncbi.nlm.nih.gov/pubmed/33878031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.202869
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