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Genetic effect of MTHFR C677T, A1298C, and A1793G polymorphisms on the age at onset, plasma homocysteine, and white matter lesions in Alzheimer's disease in the Chinese population

Background: Three polymorphisms in the Methylenetetrahydrofolate reductase (MTHFR) gene (C677T, A1298C, and A1793G) were reported associated with AD. However, their genotype distributions and associations with age at onset (AAO), homocysteine, and white matter lesions (WML) were unclear in the Chine...

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Publicado en:Aging (Albany NY)
Autores principales: Jiang, Yaling, Xiao, Xuewen, Wen, Yafei, Wan, Meidan, Zhou, Lu, Liu, Xixi, Wang, Xin, Guo, Lina, Liu, Hui, Zhou, Yafang, Wang, Junling, Liao, Xinxin, Shen, Lu, Jiao, Bin
Formato: Artigo
Lenguaje:Inglês
Publicado: Impact Journals 2021
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC8109119/
https://ncbi.nlm.nih.gov/pubmed/33833133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.202827
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