Neoadjuvant immunoradiotherapy results in high rate of complete pathological response and clinical to pathological downstaging in locally advanced head and neck squamous cell carcinoma

BACKGROUND: Checkpoint inhibitors targeting programmed death receptor-1 (PD-1) have been tested in the neoadjuvant setting for the treatment of locoregionally advanced head and neck squamous cell carcinoma (HNSCC); however, response rates are modest. We hypothesized that adding stereotactic body rad...

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Vydáno v:J Immunother Cancer
Hlavní autoři: Leidner, Rom, Crittenden, Marka, Young, Kristina, Xiao, Hong, Wu, Yaping, Couey, Marcus A, Patel, Ashish A, Cheng, Allen C, Watters, Amber L, Bifulco, Carlo, Morris, George, Rushforth, Lessli, Nemeth, Shorin, Urba, Walter J, Gough, Michael, Bell, R Bryan
Médium: Artigo
Jazyk:Inglês
Vydáno: BMJ Publishing Group 2021
Témata:
Clinical/Translational Cancer Immunotherapy
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8108690/
https://ncbi.nlm.nih.gov/pubmed/33963014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jitc-2021-002485
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