Type 1 innate lymphoid cells protect mice from acute liver injury via interferon-γ secretion for upregulating Bcl-xL expression in hepatocytes

Although type 1 innate lymphoid cells (ILC1) have been originally found as liver-resident ILC, their pathophysiological role in the liver remains poorly investigated. Here we demonstrated that carbon tetrachloride (CCl(4)) injection into mice activated ILC1, but not natural killer (NK) cells, in the...

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Udgivet i:Immunity
Main Authors: Nabekura, Tsukasa, Riggan, Luke, Hildreth, Andrew D., O’Sullivan, Timothy E., Shibuya, Akira
Format: Artigo
Sprog:Inglês
Udgivet: 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8108607/
https://ncbi.nlm.nih.gov/pubmed/31810881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2019.11.004
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