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Type 1 innate lymphoid cells protect mice from acute liver injury via interferon-γ secretion for upregulating Bcl-xL expression in hepatocytes

Although type 1 innate lymphoid cells (ILC1) have been originally found as liver-resident ILC, their pathophysiological role in the liver remains poorly investigated. Here we demonstrated that carbon tetrachloride (CCl(4)) injection into mice activated ILC1, but not natural killer (NK) cells, in the...

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Detalhes bibliográficos
Publicado no:Immunity
Main Authors: Nabekura, Tsukasa, Riggan, Luke, Hildreth, Andrew D., O’Sullivan, Timothy E., Shibuya, Akira
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8108607/
https://ncbi.nlm.nih.gov/pubmed/31810881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2019.11.004
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