Determinants of telomere length across human tissues

Telomere shortening is a hallmark of aging. Telomere length (TL) in blood cells has been studied extensively as a biomarker of human aging and disease; however, little is known regarding variability in TL in nonblood, disease-relevant tissue types. Here, we characterize variability in TLs from 6391...

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Veröffentlicht in:Science
Hauptverfasser: Demanelis, Kathryn, Jasmine, Farzana, Chen, Lin S., Chernoff, Meytal, Tong, Lin, Delgado, Dayana, Zhang, Chenan, Shinkle, Justin, Sabarinathan, Mekala, Lin, Hannah, Ramirez, Eduardo, Oliva, Meritxell, Kim-Hellmuth, Sarah, Stranger, Barbara E., Lai, Tsung-Po, Aviv, Abraham, Ardlie, Kristin G., Aguet, François, Ahsan, Habibul, Doherty, Jennifer A., Kibriya, Muhammad G., Pierce, Brandon L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8108546/
https://ncbi.nlm.nih.gov/pubmed/32913074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aaz6876
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