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Strategies for Bacteriophage T5 Mutagenesis: Expanding the Toolbox for Phage Genome Engineering

Phage genome editing is crucial to uncover the molecular mechanisms of virus infection and to engineer bacteriophages with enhanced antibacterial properties. Phage genetic engineering relies mostly on homologous recombination (HR) assisted by the targeted elimination of wild-type phages by CRISPR-Ca...

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Detalhes bibliográficos
Publicado no:Front Microbiol
Main Authors: Ramirez-Chamorro, Luis, Boulanger, Pascale, Rossier, Ombeline
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8108384/
https://ncbi.nlm.nih.gov/pubmed/33981295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2021.667332
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