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Quantum biochemistry, molecular docking, and dynamics simulation revealed synthetic peptides induced conformational changes affecting the topology of the catalytic site of SARS-CoV-2 main protease

The recent outbreak caused by SARS-CoV-2 continues to threat and take many lives all over the world. The lack of an efficient pharmacological treatments are serious problems to be faced by scientists and medical staffs worldwide. In this work, an in silico approach based on the combination of molecu...

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Detalhes bibliográficos
Publicado no:J Biomol Struct Dyn
Main Authors: Amaral, Jackson L., Oliveira, Jose T. A., Lopes, Francisco E. S., Freitas, Cleverson D. T., Freire, Valder N., Abreu, Leonardo V., Souza, Pedro F. N.
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8108194/
https://ncbi.nlm.nih.gov/pubmed/33949286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/07391102.2021.1920464
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