Let-7b-3p inhibits tumor growth and metastasis by targeting the BRF2-mediated MAPK/ERK pathway in human lung adenocarcinoma

BACKGROUND: Lung cancer is a malignant tumor with the highest morbidity and mortality rates worldwide, of which lung adenocarcinoma (LUAD) is the most common subtype. Overall, current treatments of LUAD are not satisfactory; therefore, novel targets need to be explored. Let-7b-3p is an important mem...

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Veröffentlicht in:Transl Lung Cancer Res
Hauptverfasser: Li, Yongmeng, Dong, Rui, Lu, Ming, Cheng, Chuanle, Feng, Zitong, Zhao, Renchang, Liang, Jinghui, Han, Jingyi, Jiang, Jin, Xu-Welliver, Meng, Renaud, Stéphane, Tian, Hui
Format: Artigo
Sprache:Inglês
Veröffentlicht: AME Publishing Company 2021
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8107730/
https://ncbi.nlm.nih.gov/pubmed/34012797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21037/tlcr-21-299
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