Intra-Coronary Administration of Tacrolimus Improves Myocardial Perfusion and Left Ventricular Function in Patients with ST-Segment Elevation Myocardial Infarction (COAT-STEMI) Undergoing Primary Percutaneous Coronary Intervention

BACKGROUND: Ischemia-reperfusion injury following acute ST-segment elevation myocardial infarction (STEMI) is strongly related to inflammation. However, whether intracoronary (IC) tacrolimus, an immunosuppressant, can improve myocardial perfusion is uncertain. METHODS: A multicenter double-blind ran...

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Veröffentlicht in:Acta Cardiol Sin
Hauptverfasser: Sung, Pei-Hsun, Huang, Wei-Chun, Chao, Ting-Hsing, Lee, Cheng-Han, Yang, Teng-Yao, Lin, Yu-Sheng, Chang, Rei-Yeuh, Chong, Jun-Ted, Yang, Cheng-Hsu, Chen, Chieh-Jen, Chung, Sheng-Ying, Hsueh, Shu-Kai, Wu, Chiung-Jen, Yip, Hon-Kan
Format: Artigo
Sprache:Inglês
Veröffentlicht: Taiwan Society of Cardiology 2021
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8107710/
https://ncbi.nlm.nih.gov/pubmed/33976507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.6515/ACS.202105_37(3).20201025C
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