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Novel nanopolymer RNA therapeutics normalize human diabetic corneal wound healing and epithelial stem cells

Human diabetic corneas develop delayed wound healing, epithelial stem cell dysfunction, recurrent erosions, and keratitis. Adenoviral gene therapy modulating c-Met, cathepsin F and MMP-10 normalized wound healing and epithelial stem cells in organ-cultured diabetic corneas but showed toxicity in ste...

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Bibliografiska uppgifter
I publikationen:Nanomedicine
Huvudupphovsmän: Kramerov, Andrei A., Shah, Ruchi, Ding, Hui, Holler, Eggehard, Turjman, Sue, Rabinowitz, Yaron S., Ghiam, Sean, Maguen, Ezra, Svendsen, Clive N., Saghizadeh, Mehrnoosh, Ljubimova, Julia Y., Ljubimov, Alexander V.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2020
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC8107190/
https://ncbi.nlm.nih.gov/pubmed/33181273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nano.2020.102332
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