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Novel nanopolymer RNA therapeutics normalize human diabetic corneal wound healing and epithelial stem cells
Human diabetic corneas develop delayed wound healing, epithelial stem cell dysfunction, recurrent erosions, and keratitis. Adenoviral gene therapy modulating c-Met, cathepsin F and MMP-10 normalized wound healing and epithelial stem cells in organ-cultured diabetic corneas but showed toxicity in ste...
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| Veröffentlicht in: | Nanomedicine |
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| Hauptverfasser: | , , , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2020
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8107190/ https://ncbi.nlm.nih.gov/pubmed/33181273 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nano.2020.102332 |
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