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Intragastric and atomized administration of canagliflozin inhibit inflammatory cytokine storm in lipopolysaccharide-treated sepsis in mice: A potential COVID-19 treatment

To date, drugs to attenuate cytokine storm in severe cases of Corona Virus Disease 2019 (COVID-19) are not available. In this study, we investigated the effects of intragastric and atomized administration of canagliflozin (CAN) on cytokine storm in lung tissues of lipopolysaccharides (LPS)-induced m...

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Detalhes bibliográficos
Publicado no:Int Immunopharmacol
Main Authors: Niu, Yaoyun, Chen, Yang, Sun, Pengbo, Wang, Yangyang, Luo, Jingyi, Ding, Yipei, Xie, Weidong
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier B.V. 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8106881/
https://ncbi.nlm.nih.gov/pubmed/34020392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.intimp.2021.107773
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