Xpert MTB/XDR: a 10-Color Reflex Assay Suitable for Point-of-Care Settings To Detect Isoniazid, Fluoroquinolone, and Second-Line-Injectable-Drug Resistance Directly from Mycobacterium tuberculosis-Positive Sputum

We describe the design, development, analytical performance, and a limited clinical evaluation of the 10-color Xpert MTB/XDR assay (CE-IVD only, not for sale in the United States). This assay is intended as a reflex test to detect resistance to isoniazid (INH), fluoroquinolones (FLQ), ethionamide (E...

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Publicado en:J Clin Microbiol
Autores principales: Cao, Yuan, Parmar, Heta, Gaur, Rajiv L., Lieu, Deanna, Raghunath, Shobana, Via, Nova, Battaglia, Simone, Cirillo, Daniela M., Denkinger, Claudia, Georghiou, Sophia, Kwiatkowski, Robert, Persing, David, Alland, David, Chakravorty, Soumitesh
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2021
Materias:
Mycobacteriology and Aerobic Actinomycetes
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC8106700/
https://ncbi.nlm.nih.gov/pubmed/33298611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.02314-20
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