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Gαi1 Promoted Proliferation, Migration and Invasion via Activating the Akt-mTOR/Erk-MAPK Signaling Pathway in Renal Cell Carcinoma
BACKGROUND: Renal cell carcinoma (RCC) accounts for about 2–3% of all adult malignancies. G protein alpha inhibitory subunit 1 (Gαi1) plays a key role in mediating PI3K-Akt signaling upon activation of receptor tyrosine kinases (RTKs). However, little is known about its expression, regulation and bi...
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| Publicado no: | Onco Targets Ther |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Dove
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8106533/ https://ncbi.nlm.nih.gov/pubmed/33976552 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S298102 |
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