Mechanisms of repeat-associated non-AUG translation in neurological microsatellite expansion disorders

Repeat-associated non-AUG (RAN) translation was discovered in 2011 in spinocerebellar ataxia type 8 (SCA8) and myotonic dystrophy type 1 (DM1). This non-canonical form of translation occurs in all reading frames from both coding and non-coding regions of sense and antisense transcripts carrying expa...

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Bibliographic Details
Published in:Biochem Soc Trans
Main Authors: Castelli, Lydia M., Huang, Wan-Ping, Lin, Ya-Hui, Chang, Kung-Yao, Hautbergue, Guillaume M.
Format: Artigo
Language:Inglês
Published: Portland Press Ltd. 2021
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Review Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8106499/
https://ncbi.nlm.nih.gov/pubmed/33729487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BST20200690
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