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COVIDOUTCOME—estimating COVID severity based on mutation signatures in the SARS-CoV-2 genome

Numerous studies demonstrate frequent mutations in the genome of SARS-CoV-2. Our goal was to statistically link mutations to severe disease outcome. We used an automated machine learning approach where 1594 viral genomes with available clinical follow-up data were used as the training set (797 ‘seve...

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Detalhes bibliográficos
Publicado no:Database (Oxford)
Main Authors: Nagy, Ádám, Ligeti, Balázs, Szebeni, János, Pongor, Sándor, Győrffy, Balázs
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8106440/
https://ncbi.nlm.nih.gov/pubmed/33963845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/database/baab020
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