Sunitinib malate-loaded biodegradable microspheres for the prevention of corneal neovascularization in rats

Corneal neovascularization (NV) predisposes patients to compromised corneal transparency and visional acuity. Sunitinib malate (Sunb-malate) targeting against multiple receptor tyrosine kinases, exerts potent antiangiogenesis. However, the rapid clearance of Sunb-malate eye drops administered throug...

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Vydáno v:J Control Release
Hlavní autoři: Yang, Jin, Luo, Lixia, Oh, Yumin, Meng, Tuo, Chai, Guihong, Xia, Shiyu, Emmert, David, Wang, Bing, Eberhart, Charles G., Lee, Seulki, Stark, Walter J., Ensign, Laura M., Hanes, Justin, Xu, Qingguo
Médium: Artigo
Jazyk:Inglês
Vydáno: 2020
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8105765/
https://ncbi.nlm.nih.gov/pubmed/32822742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2020.08.019
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