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Lipid interactions of an actinoporin pore-forming oligomer

The actinoporins are cytolytic toxins produced by sea anemones. Upon encountering a membrane, preferably containing sphingomyelin, they oligomerize and insert their N-terminal helix into the membrane, forming a pore. Whether sphingomyelin is specifically recognized by the protein or simply induces p...

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Bibliografiske detaljer
Udgivet i:Biophys J
Main Authors: Sepehri, Aliasghar, Nepal, Binod, Lazaridis, Themis
Format: Artigo
Sprog:Inglês
Udgivet: The Biophysical Society 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8105734/
https://ncbi.nlm.nih.gov/pubmed/33617834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2021.02.015
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