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Probing E. coli SSB protein-DNA topology by reversing DNA backbone polarity

Escherichia coli single-strand (ss) DNA binding protein (SSB) is an essential protein that binds ssDNA intermediates formed during genome maintenance. SSB homotetramers bind ssDNA in two major modes, differing in occluded site size and cooperativity. The (SSB)(35) mode in which ssDNA wraps, on avera...

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Bibliografiske detaljer
Udgivet i:Biophys J
Main Authors: Kozlov, Alexander G., Lohman, Timothy M.
Format: Artigo
Sprog:Inglês
Udgivet: The Biophysical Society 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8105733/
https://ncbi.nlm.nih.gov/pubmed/33636169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2021.02.025
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