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CXCR4-binding PET tracers link monocyte recruitment and endothelial injury in murine atherosclerosis

OBJECTIVE: Viral macrophage inflammatory protein 2 (vMIP-II/vCCL2) binds to multiple chemokine receptors, and vMIP-II based PET tracer ((64)Cu-DOTA-vMIP-II: vMIP-II tracer) accumulates at atherosclerotic lesions in mice. Given that it would be expected to react with multiple chemokine receptors on m...

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Detalhes bibliográficos
Publicado no:Arterioscler Thromb Vasc Biol
Main Authors: Baba, Osamu, Huang, Li-Hao, Elvington, Andrew, Szpakowska, Martyna, Sultan, Deborah, Heo, Gyu Seong, Zhang, Xiaohui, Luehmann, Hannah, Detering, Lisa, Chevigné, Andy, Liu, Yongjian, Randolph, Gwendalyn J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8105279/
https://ncbi.nlm.nih.gov/pubmed/33327748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.120.315053
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