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Ongoing repair of migration-coupled DNA damage allows planarian adult stem cells to reach wound sites

Mechanical stress during cell migration may be a previously unappreciated source of genome instability, but the extent to which this happens in any animal in vivo remains unknown. We consider an in vivo system where the adult stem cells of planarian flatworms are required to migrate to a distal woun...

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Detalles Bibliográficos
Publicado en:eLife
Main Authors: Sahu, Sounak, Sridhar, Divya, Abnave, Prasad, Kosaka, Noboyoshi, Dattani, Anish, Thompson, James M, Hill, Mark A, Aboobaker, Aziz
Formato: Artigo
Idioma:Inglês
Publicado: eLife Sciences Publications, Ltd 2021
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8104965/
https://ncbi.nlm.nih.gov/pubmed/33890575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.63779
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