Antibody Screening System Using a Herpes Simplex Virus (HSV)-Based Probe To Identify a Novel Target for Receptor-Retargeted Oncolytic HSVs

Herpes simplex virus (HSV) is a promising tool for developing oncolytic virotherapy. We recently reported a platform for receptor-retargeted oncolytic HSVs that incorporates single-chain antibodies (scFvs) into envelope glycoprotein D (gD) to mediate virus entry via tumor-associated antigens. Theref...

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Bibliographic Details
Published in:J Virol
Main Authors: Ikeda, Hitomi, Uchida, Hiroaki, Okubo, Yu, Shibata, Tomoko, Sasaki, Yasuhiko, Suzuki, Takuma, Hamada-Uematsu, Mika, Hamasaki, Ryota, Okuda, Kosaku, Yamaguchi, Miki, Kojima, Masaki, Tanaka, Masato, Hamada, Hirofumi, Tahara, Hideaki
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2021
Subjects:
Virus-Cell Interactions
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8104110/
https://ncbi.nlm.nih.gov/pubmed/33627393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01766-20
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