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Porcine Epidemic Diarrhea Virus Infection Induces Caspase-8-Mediated G3BP1 Cleavage and Subverts Stress Granules To Promote Viral Replication

Porcine epidemic diarrhea virus (PEDV) is an α-coronavirus causing severe diarrhea and high mortality rates in suckling piglets and posing significant economic impact. PEDV replication is completed and results in a large amount of RNA in the cytoplasm. Stress granules (SGs) are dynamic cytosolic RNA...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:J Virol
Hauptverfasser: Sun, Liumei, Chen, Huan, Ming, Xin, Bo, Zongyi, Shin, Hyun-Jin, Jung, Yong-Sam, Qian, Yingjuan
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2021
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8104091/
https://ncbi.nlm.nih.gov/pubmed/33568512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02344-20
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