scSNV: accurate dscRNA-seq SNV co-expression analysis using duplicate tag collapsing

Identifying single nucleotide variants has become common practice for droplet-based single-cell RNA-seq experiments; however, presently, a pipeline does not exist to maximize variant calling accuracy. Furthermore, molecular duplicates generated in these experiments have not been utilized to optimall...

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Bibliografiske detaljer
Udgivet i:Genome Biol
Main Authors: Wilson, Gavin W., Derouet, Mathieu, Darling, Gail E., Yeung, Jonathan C.
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2021
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Method
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8103760/
https://ncbi.nlm.nih.gov/pubmed/33962667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-021-02364-5
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