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Giantin is required for intracellular N-terminal processing of type I procollagen

Knockout of the golgin giantin leads to skeletal and craniofacial defects driven by poorly studied changes in glycosylation and extracellular matrix deposition. Here, we sought to determine how giantin impacts the production of healthy bone tissue by focusing on the main protein component of the ost...

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Detalhes bibliográficos
Publicado no:J Cell Biol
Main Authors: Stevenson, Nicola L., Bergen, Dylan J.M., Lu, Yinhui, Prada-Sanchez, M. Esther, Kadler, Karl E., Hammond, Chrissy L., Stephens, David J.
Formato: Artigo
Idioma:Inglês
Publicado em: Rockefeller University Press 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8103548/
https://ncbi.nlm.nih.gov/pubmed/33944912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.202005166
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