Intrapatient comparisons of efficacy in a single-arm trial of entrectinib in tumour-agnostic indications

BACKGROUND: Entrectinib is a tropomyosin receptor kinase inhibitor approved for the treatment of neurotrophic tyrosine receptor kinase (NTRK) fusion-positive solid tumours based on single-arm trials. Traditional randomised clinical trials in rare cancers are not feasible; we conducted an intrapatien...

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Detalhes bibliográficos
Publicado no:ESMO Open
Main Authors: Krebs, M.G., Blay, J.-Y., Le Tourneau, C., Hong, D., Veronese, L., Antoniou, M., Bennett, I.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2021
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Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8103537/
https://ncbi.nlm.nih.gov/pubmed/33676294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.esmoop.2021.100072
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