Evaluation of Trials Comparing Single-Enantiomer Drugs to Their Racemic Precursors: A Systematic Review

IMPORTANCE: Chiral switching, a strategy in which drug manufacturers develop a single-enantiomer formulation of a drug to be substituted for a racemic formulation, allows manufacturers to maintain market exclusivity for drugs losing patent protection, even without demonstrating superior efficacy or...

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Foilsithe in:JAMA Netw Open
Main Authors: Long, Aaron S., Zhang, Audrey D., Meyer, Caitlin E., Egilman, Alexander C., Ross, Joseph S., Wallach, Joshua D.
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Medical Association 2021
Ábhair:
Original Investigation
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8103227/
https://ncbi.nlm.nih.gov/pubmed/33956134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamanetworkopen.2021.5731
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