Myeloid‐resident neuropilin‐1 promotes choroidal neovascularization while mitigating inflammation

Age‐related macular degeneration (AMD) in its various forms is a leading cause of blindness in industrialized countries. Here, we provide evidence that ligands for neuropilin‐1 (NRP1), such as Semaphorin 3A and VEGF‐A, are elevated in the vitreous of patients with AMD at times of active choroidal ne...

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Pubblicato in:EMBO Mol Med
Autori principali: Andriessen, Elisabeth M M A, Binet, François, Fournier, Frédérik, Hata, Masayuki, Dejda, Agnieszka, Mawambo, Gaëlle, Crespo‐Garcia, Sergio, Pilon, Frédérique, Buscarlet, Manuel, Beauchemin, Karine, Bougie, Véronique, Cumberlidge, Garth, Wilson, Ariel M, Bourgault, Steve, Rezende, Flavio A, Beaulieu, Normand, Delisle, Jean‐Sébastien, Sapieha, Przemyslaw
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8103107/
https://ncbi.nlm.nih.gov/pubmed/33876574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/emmm.201911754
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