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Oxidative Stress in SLE T Cells, Is NRF2 Really the Target to Treat?

Oxidative stress is a major component of cellular damage in T cells from patients with systemic lupus erythematosus (SLE) resulting amongst others in the generation of pathogenic Th17 cells. The NRF2/Keap1 pathway is the most important antioxidant system protecting cells from damage due to oxidative...

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Détails bibliographiques
Publié dans:Front Immunol
Auteurs principaux: Ohl, Kim, Tenbrock, Klaus
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2021
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8102865/
https://ncbi.nlm.nih.gov/pubmed/33968025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.633845
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