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Leptin Receptor, a Surface Marker for a Subset of Highly Engrafting Long-term Functional Hematopoietic Stem Cells

The hematopoietic system is sustained by a rare population of hematopoietic stem cells (HSCs), which emerge during early embryonic development and then reside in the hypoxic niche of the adult bone marrow microenvironment. Although leptin receptor (Lepr)-expressing stromal cells are well-studied as...

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Dettagli Bibliografici
Pubblicato in:Leukemia
Autori principali: Trinh, Thao, Ropa, James, Aljoufi, Arafat, Cooper, Scott, Sinn, Anthony, Srour, Edward F., Broxmeyer, Hal E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8102644/
https://ncbi.nlm.nih.gov/pubmed/33159180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41375-020-01079-z
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