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Cytochrome P450-epoxygenated fatty acids inhibit Müller glial inflammation

Free fatty acid dysregulation in diabetics may elicit the release of inflammatory cytokines from Müller cells (MC), promoting the onset and progression of diabetic retinopathy (DR). Palmitic acid (PA) is elevated in the sera of diabetics and stimulates the production of the DR-relevant cytokines by...

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Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Ontko, Cayla D., Capozzi, Megan E., Kim, Minjae J., McCollum, Gary W., Penn, John S.
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2021
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8102485/
https://ncbi.nlm.nih.gov/pubmed/33958662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-89000-1
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