IgG intrathecal synthesis in HIV-associated neurocognitive disorder (HAND) according to the HIV-1 subtypes and pattern of HIV RNA in CNS and plasma compartments

We hypothesized that humoral immunity stimulation in the CNS in HIV-1C patients would be lower than that in HIV-1B due to a defective Tat chemokine dimotif (C30C31) that might influence cellular trafficking and CNS inflammation. Sixty-eight paired CSF and blood samples from people with HIV (PWH), fr...

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Vydáno v:J Neuroimmunol
Hlavní autoři: De Almeida, Sergio M., Rotta, Indianara, Tang, Bin, Vaida, Florin, Letendre, Scott, Ellis, Ronald J.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2021
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8102367/
https://ncbi.nlm.nih.gov/pubmed/33845284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jneuroim.2021.577542
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