High detection rates of pancreatic cancer across stages by plasma assay of novel methylated DNA markers and CA 19-9

BACKGROUND & AIMS: We have previously identified tissue methylated DNA markers (MDMs) associated with pancreatic ductal adenocarcinoma (PDAC). In this case-control study, we aimed to assess the diagnostic performance of plasma MDMs for PDAC. METHODS: Thirteen MDMs (GRIN2D, CD1D, ZNF781, FER1L4,...

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Udgivet i:Clin Cancer Res
Main Authors: Majumder, Shounak, Taylor, William R., Foote, Patrick H., Berger, Calise K., Wu, Chung Wah, Mahoney, Douglas W., Bamlet, William R., Burger, Kelli N., Postier, Neil, de la Fuente, Jaime, Doering, Karen A., Lidgard, Graham P., Allawi, Hatim T., Petersen, Gloria M., Chari, Suresh T., Ahlquist, David A., Kisiel, John B.
Format: Artigo
Sprog:Inglês
Udgivet: 2021
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8102343/
https://ncbi.nlm.nih.gov/pubmed/33593879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-20-0235
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