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Targeting EYA3 in Ewing Sarcoma Retards Tumor Growth and Angiogenesis

EWSR1/FLI1, the most common fusion gene in Ewing sarcoma, upregulates expression of the Eyes Absent 3 (EYA3) transactivator–phosphatase protein. The purpose of this study was to investigate molecular and cellular mechanisms through which EYA3 might promote Ewing sarcoma tumor growth and to determine...

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Detaylı Bibliyografya
Yayımlandı:Mol Cancer Ther
Asıl Yazarlar: Wang, Yuhua, Pandey, Ram Naresh, Roychoudhury, Kaushik, Milewski, David, Kalin, Tanya V, Szabo, Sara, Pressey, Joseph G, Hegde, Rashmi S.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2021
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC8102334/
https://ncbi.nlm.nih.gov/pubmed/33649104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-20-0749
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