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Prolonged Low-Dose Dioxin Exposure Impairs Metabolic Adaptability to High-Fat Diet Feeding in Female but Not Male Mice

CONTEXT: Human studies consistently show an association between exposure to persistent organic pollutants, including 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD, aka “dioxin”), and increased diabetes risk. We previously showed that a single high-dose TCDD exposure (20 µg/kg) decreased plasma insulin l...

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Bibliografiske detaljer
Udgivet i:Endocrinology
Main Authors: Matteo, Geronimo, Hoyeck, Myriam P, Blair, Hannah L, Zebarth, Julia, Rick, Kayleigh R C, Williams, Andrew, Gagné, Rémi, Buick, Julie K, Yauk, Carole L, Bruin, Jennifer E
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2021
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8101695/
https://ncbi.nlm.nih.gov/pubmed/33693622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/endocr/bqab050
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