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Prioritization of Osteoporosis‐Associated Genome‐wide Association Study (GWAS) Single‐Nucleotide Polymorphisms (SNPs) Using Epigenomics and Transcriptomics

Genetic risk factors for osteoporosis, a prevalent disease associated with aging, have been examined in many genome‐wide association studies (GWASs). A major challenge is to prioritize transcription‐regulatory GWAS‐derived variants that are likely to be functional. Given the critical role of epigene...

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Bibliografski detalji
Izdano u:JBMR Plus
Glavni autori: Zhang, Xiao, Deng, Hong‐Wen, Shen, Hui, Ehrlich, Melanie
Format: Artigo
Jezik:Inglês
Izdano: John Wiley & Sons, Inc. 2021
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8101624/
https://ncbi.nlm.nih.gov/pubmed/33977200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbm4.10481
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