ALK1 regulates the internalization of endoglin and the type III TGF-β receptor

Complex formation and endocytosis of transforming growth factor-β (TGF-β) receptors play important roles in signaling. However, their interdependence remained unexplored. Here, we demonstrate that ALK1, a TGF-β type I receptor prevalent in endothelial cells, forms stable complexes at the cell surfac...

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Bibliografiske detaljer
Udgivet i:Mol Biol Cell
Main Authors: Tazat, Keren, Pomeraniec-Abudy, Leslie, Hector-Greene, Melissa, Szilágyi, Szabina Szófia, Sharma, Swati, Cai, Elise M., Corona, Armando L., Ehrlich, Marcelo, Blobe, Gerard C., Henis, Yoav I.
Format: Artigo
Sprog:Inglês
Udgivet: The American Society for Cell Biology 2021
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8101464/
https://ncbi.nlm.nih.gov/pubmed/33566682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E20-03-0199
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