Sustained Inhibition of NF-κB Activity Mitigates Retinal Vasculopathy in Diabetes

This study investigated the effects of long-term NF-κB inhibition in mitigating retinal vasculopathy in a type 1 diabetic mouse model (Akita, Ins2(Akita)). Akita and wild-type (C57BL/6J) male mice, 24 to 26 weeks old, were treated with or without a selective inhibitor of NF-κB, 4-methyl-N1-(3-phenyl...

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Udgivet i:Am J Pathol
Main Authors: Homme, Rubens P., Sandhu, Harpal S., George, Akash K., Tyagi, Suresh C., Singh, Mahavir
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Investigative Pathology 2021
Fag:
Regular Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8101051/
https://ncbi.nlm.nih.gov/pubmed/33640319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2021.01.016
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