Hydroxytyrosol Acetate Inhibits Vascular Endothelial Cell Pyroptosis via the HDAC11 Signaling Pathway in Atherosclerosis

Hydroxytyrosol acetate (HT-AC), a natural polyphenolic compound in olive oil, exerts an anti-inflammatory effect in cardiovascular diseases (CVDs). Pyroptosis is a newly discovered form of programmed inflammatory cell death and is suggested to be involved in the atherosclerosis (AS) process. However...

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Vydáno v:Front Pharmacol
Hlavní autoři: Yao, Feng, Jin, Zhen, Lv, Xiaohan, Zheng, Zihan, Gao, Hongqian, Deng, Ying, Liu, Yizhen, Chen, Lifang, Wang, Weirong, He, Jianyu, Gu, Jianli, Lin, Rong
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2021
Témata:
Pharmacology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8100680/
https://ncbi.nlm.nih.gov/pubmed/33967800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2021.656272
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