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Transport of Drugs and Endogenous Compounds Mediated by Human OCT1: Studies in Single- and Double-Transfected Cell Models

Organic Cation Transporter 1 (OCT1, gene symbol: SLC22A1) is predominately expressed in human liver, localized in the basolateral membrane of hepatocytes and facilitates the uptake of endogenous compounds (e.g. serotonin, acetylcholine, thiamine), and widely prescribed drugs (e.g. metformin, fenoter...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Front Pharmacol
मुख्य लेखकों: Haberkorn, Bastian, Fromm, Martin F., König, Jörg
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Frontiers Media S.A. 2021
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC8100673/
https://ncbi.nlm.nih.gov/pubmed/33967805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2021.662535
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