Pro-Resolving Mediator Annexin A1 Regulates Intracellular Ca(2+) and Mucin Secretion in Cultured Goblet Cells Suggesting a New Use in Inflammatory Conjunctival Diseases

The amount of mucin secreted by conjunctival goblet cells is regulated to ensure the optimal level for protection of the ocular surface. Under physiological conditions lipid specialized pro-resolving mediators (SPM) are essential for maintaining tissue homeostasis including the conjunctiva. The prot...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Lyngstadaas, Anne V., Olsen, Markus V., Bair, Jeffrey A., Hodges, Robin R., Utheim, Tor P., Serhan, Charles N., Dartt, Darlene A.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8100605/
https://ncbi.nlm.nih.gov/pubmed/33968020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.618653
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