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PD-L1 Blockade During Allergen Sensitization Inhibits the Synthesis of Specific Antibodies and Decreases Mast Cell Activation in a Murine Model of Active Cutaneous Anaphylaxis

Programmed cell death ligand 1(PDL-1) is known for its inhibitory effect on the cellular immune response. Even though it is expressed on the surface of mast cells, its role in allergic diseases is unknown. We analyzed the effects of PD-L1 blockade in a murine model of active cutaneous anaphylaxis (A...

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Vydáno v:Front Immunol
Hlavní autoři: Bonamichi-Santos, Rafael, Aun, Marcelo Vivolo, Kalil, Jorge, Castells, Mariana Concepcion, Giavina-Bianchi, Pedro
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2021
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8100332/
https://ncbi.nlm.nih.gov/pubmed/33968057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.655958
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